HBV viremia linked to progression of dysplastic nodules to HCC
Patients with dysplastic nodules due to chronic hepatitis B infection were more likely to progress to hepatocellular carcinoma with higher HBV viral loads in a study presented at the International Liver Cancer Association Annual Conference in Washington, DC.
Researchers evaluated clinical, radiologic and laboratory data from 52 patients with intrahepatic dysplastic nodules (DN) resulting from chronic hepatitis B, between January 2003 and December 2012, with a median follow-up of 26 months. The mean age of the cohort (71% men) was 59.1 years. Patients had a mean of 1.78 ± 1.2 DNs, with a mean size of 1 ± 0.1 cm per nodule. DNs were detected and diagnosed via abdominal computed tomography.