A small study, presented at the 2014 Liver Congress found that HBeAg-positive children who were treated with vitamin E (15 mg/kg/daily) for 12 months achieved higher rates of HBeAg conversion, lower viral loads and normal ALT levels than did untreated children.
The Italian study followed 46 children treated with vitamin E for 12 months and six children who were not for a total of 24 months, including 12 months of monitoring after treatment ended.
“A complete response (normal ALT levels and HBV DNA under 2,000 IU/mL) was achieved in eight of the 23 children treated with vitamin E (33%) compared to only one of 23 children who were not treated (4%).
HBeAg seroconversion was also higher in the vitamin E-treated group, however specific numbers were not included in the abstract’s description of the study. (Abstract P1088)
HBV Journal Review
May 1, 2014, Vol 11, no 5